Spyre Therapeutics Down over 12%, on Pace for Largest Percent Decrease Since June 2024

Dow Jones

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Spyre Therapeutics, Inc (SYRE) is currently at $94.12, down $13.24 or 12.33%

--Would be lowest close since July 16, 2026, when it closed at $94.12

--On pace for largest percent decrease since June 17, 2024, when it fell 19.3%

--Snaps a two day winning streak

--Down 4.28% month-to-date; on pace for worst month since April 2025, when it fell 5.61%

--Up 187.3% year-to-date

--Down 68.6% from its all-time closing high of $299.75 on April 8, 2016

--Up 449.12% from 52 weeks ago (Aug. 27, 2025), when it closed at $17.14

--Down 13.59% from its 52-week closing high of $108.92 on Aug. 19, 2026

--Up 535.09% from its 52-week closing low of $14.82 on Sept. 16, 2025

--Traded as low as $90.60; lowest intraday level since July 7, 2026, when it hit $86.60

--Down 15.61% at today's intraday low; largest intraday percent decrease since June 24, 2026, when it fell as much as 15.87%

All data as of 10:32:24 AM ET

Source: Dow Jones Market Data, FactSet

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on pace for worst month since April 2025, when it fell 5.61% \n</p>\n<p>\n       --Up 187.3% year-to-date \n</p>\n<p>\n       --Down 68.6% from its all-time closing high of $299.75 on April 8, 2016 \n</p>\n<p>\n       --Up 449.12% from 52 weeks ago (Aug. 27, 2025), when it closed at $17.14 \n</p>\n<p>\n       --Down 13.59% from its 52-week closing high of $108.92 on Aug. 19, 2026 \n</p>\n<p>\n       --Up 535.09% from its 52-week closing low of $14.82 on Sept. 16, 2025 \n</p>\n<p>\n       --Traded as low as $90.60; lowest intraday level since July 7, 2026, when it hit $86.60 \n</p>\n<p>\n       --Down 15.61% at today's intraday low; largest intraday percent decrease since June 24, 2026, when it fell as much as 15.87% \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n     All data as of 10:32:24 AM ET \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n     Source: Dow Jones Market Data, FactSet \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n</font>","source":null,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; 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overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nSpyre Therapeutics Down over 12%, on Pace for Largest Percent Decrease Since June 2024\n</h2>\n\n<h4 class=\"meta\">\n\n\n<div class=\"head\" \">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/150f88aa4d182df19190059f4a365e99);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Dow Jones </p>\n<p class=\"h-time\">2026-08-26 22:35</p>\n</div>\n\n</div>\n\n\n</h4>\n\n</header>\n<article>\n<font class=\"NormalMinus1\" face=\"Arial\">\n<p>\n  <a href=\"https://laohu8.com/S/SYRE\">Spyre Therapeutics</a>, Inc (SYRE) is currently at $94.12, down $13.24 or 12.33% \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n       --Would be lowest close since July 16, 2026, when it closed at $94.12 \n</p>\n<p>\n       --On pace for largest percent decrease since June 17, 2024, when it fell 19.3% \n</p>\n<p>\n       --Snaps a two day winning streak \n</p>\n<p>\n       --Down 4.28% month-to-date; on pace for worst month since April 2025, when it fell 5.61% \n</p>\n<p>\n       --Up 187.3% year-to-date \n</p>\n<p>\n       --Down 68.6% from its all-time closing high of $299.75 on April 8, 2016 \n</p>\n<p>\n       --Up 449.12% from 52 weeks ago (Aug. 27, 2025), when it closed at $17.14 \n</p>\n<p>\n       --Down 13.59% from its 52-week closing high of $108.92 on Aug. 19, 2026 \n</p>\n<p>\n       --Up 535.09% from its 52-week closing low of $14.82 on Sept. 16, 2025 \n</p>\n<p>\n       --Traded as low as $90.60; lowest intraday level since July 7, 2026, when it hit $86.60 \n</p>\n<p>\n       --Down 15.61% at today's intraday low; largest intraday percent decrease since June 24, 2026, when it fell as much as 15.87% \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n     All data as of 10:32:24 AM ET \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n     Source: Dow Jones Market Data, FactSet \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n</font>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK4539","symbol_name":"次新股","start_time":0,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","article_id":"2662104247","we_media_id":"106","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2662104247","pubTimestamp":1787754900,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Dow Jones","introduction":"Dow Jones publishes the world’s most trusted business news and financial information in a variety of media.","home_visible":0,"id":"106","head_image":"https://static.tigerbbs.com/150f88aa4d182df19190059f4a365e99"},"summary":"Spyre Therapeutics, Inc  is currently at $94.12, down $13.24 or 12.33%--Would be lowest close since July 16, 2026, when it closed at $94.12--On pace for largest percent decrease since June 17, 2024, when it fell 19.3%--Snaps a two day winning streak--Down 4.28% month-to-date; on pace for worst month since April 2025, when it fell 5.61%--Up 187.3% year-to-date--Down 68.6% from its all-time closing high of $299.75 on April 8, 2016--Up 449.12% from 52 weeks ago , when it closed at $17.14--Down 13.59% from its 52-week closing high of $108.92 on Aug. 19, 2026--Up 535.09% from its 52-week closing low of $14.82 on Sept. 16, 2025--Traded as low as $90.60; lowest intraday level since July 7, 2026, when it hit $86.60--Down 15.61% at today's intraday low; largest intraday percent decrease since June 24, 2026, when it fell as much as 15.87%All data as of 10:32:24 AM ETSource: Dow Jones Market Data, FactSet","collect":0,"end_time":0,"defaultTopTitle":"","property":[],"viewcount":null,"language":"en","relate_stocks":{"BK4539":"次新股","BK4139":"生物科技","LENZ":"Therapeutics","SYRE":"SPYRE THERAPEUTICS INC","BK4007":"制药","LFSC":"F/m Emerald Life Sciences Innovation ETF"},"translate_title":"Spyre Therapeutics 下跌超过 12%，有望创下 2024 年 6 月以来最大百分比跌幅","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"LFSC":0.6,"LENZ":1.5,"SYRE":1},"content_text":"Spyre Therapeutics, Inc (SYRE) is currently at $94.12, down $13.24 or 12.33% \n\n\n \n\n\n       --Would be lowest close since July 16, 2026, when it closed at $94.12 \n\n\n       --On pace for largest percent decrease since June 17, 2024, when it fell 19.3% \n\n\n       --Snaps a two day winning streak \n\n\n       --Down 4.28% month-to-date; on pace for worst month since April 2025, when it fell 5.61% \n\n\n       --Up 187.3% year-to-date \n\n\n       --Down 68.6% from its all-time closing high of $299.75 on April 8, 2016 \n\n\n       --Up 449.12% from 52 weeks ago (Aug. 27, 2025), when it closed at $17.14 \n\n\n       --Down 13.59% from its 52-week closing high of $108.92 on Aug. 19, 2026 \n\n\n       --Up 535.09% from its 52-week closing low of $14.82 on Sept. 16, 2025 \n\n\n       --Traded as low as $90.60; lowest intraday level since July 7, 2026, when it hit $86.60 \n\n\n       --Down 15.61% at today's intraday low; largest intraday percent decrease since June 24, 2026, when it fell as much as 15.87% \n\n\n \n\n\n     All data as of 10:32:24 AM ET \n\n\n \n\n\n     Source: Dow Jones Market Data, FactSet","kind":"highlight","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":true,"editions":null,"column":"","sentiment":"-2","news_tag":"","news_rank":0,"isVideo":false,"video":null,"symbols":[],"gpt_button":0,"need_auth":true,"need_login_tip":false,"code":"91000000","status":"200"}}}