This article was automatically generated using Dow Jones technology.

Shares of small-cap companies were mixed Wednesday, as the Russell 2000 Index fell 0.1%, while the S&P Small Cap 600 Index was up 0.1%.

Among companies with a market value of $1 billion to $6.7 billion, Generate Biomedicines Inc. was the biggest laggard during the session, dropping 21%, followed by shares of Evolution Metals & Technologies Corp., which dropped 15%. Shares of Advasa Holdings Inc. dropped 14%, Climb Bio Inc. shares tumbled 9.9%, and Horizon Quantum Holdings Ltd. tumbled 8.9%.

Abercrombie & Fitch Co. was the best performer, surging 36%, followed by Biohaven Ltd., which surged 18%. Seaport Therapeutics Inc. shares surged 12%, WEBTOON Entertainment Inc. surged 11%, and shares of SolarEdge Technologies Inc. jumped 11%.

Major stock indexes in the U.S. ended Wednesday mixed with the Nasdaq Composite Index dropping 0.1%. Meanwhile, the S&P 500 Index was flat, and the Dow Jones Industrial Average dropped 0.2%.

Data source: Dow Jones Market Data, FactSet